STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CBL45560.1Propionyl-CoA carboxylase; silverDB:HdN1F2607. (532 aa)    
Predicted Functional Partners:
CBL44335.1
Biotin/lipoyl attachment:Carbamoyl-phosphate synthase L chain, ATP-binding; silverDB:HdN1F975.
  
 0.947
CBL44652.1
Putative biotin carboxylase protein; silverDB:HdN1F1398.
 
 0.934
CBL45561.1
Putative enoyl-CoA hydratase; silverDB:HdN1F2608.
 
 
 0.767
birA
Biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
 
 0.741
hmgL
Hydroxymethylglutaryl-CoA lyase; silverDB:HdN1F76; Belongs to the alpha-IPM synthase/homocitrate synthase family.
 
 
 0.733
CBL45097.1
Non-ribosomal peptide synthase; silverDB:HdN1F2001.
  
 
 0.699
CBL45096.1
Non-ribosomal peptide synthetase modules and related proteins; silverDB:HdN1F1999.
  
 
 0.682
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; silverDB:HdN1F2611.
  
 
 0.632
acd
Acyl-CoA dehydrogenase, probably Isovaleryl-CoA dehydrogenase; silverDB:HdN1F4562.
 
  
 0.631
accC
Acetyl-CoA carboxylase,biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 0.609
Your Current Organism:
gamma proteobacterium HdN1
NCBI taxonomy Id: 83406
Other names: g. proteobacterium HdN1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.