STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJH39217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (519 aa)    
Predicted Functional Partners:
OJH39218.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.566
grpE
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
  
 0.501
grpE-2
Nucleotide exchange factor GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds [...]
  
  
 0.501
OJH42490.1
Peptidase S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.448
OJH39324.1
Type III secretion protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.445
OJH40719.1
Cellulose-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.443
OJH33523.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.434
OJH41646.1
APHP domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.428
Your Current Organism:
Cystobacter ferrugineus
NCBI taxonomy Id: 83449
Other names: C. ferrugineus, DSM 14716, JCM 12624, Polyangium ferrugineum, strain Cb fe18, strain Windsor M-203
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