STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OJH39549.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (69 aa)    
Predicted Functional Partners:
guaA
Glutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.739
OJH37682.1
Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family.
    
  0.736
OJH39550.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cytochrome P450 family.
       0.714
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
  0.561
OJH39548.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.535
OJH35458.1
SpoVR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.509
OJH40373.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.448
deoD
Purine-nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.420
mtnP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
    
  0.400
Your Current Organism:
Cystobacter ferrugineus
NCBI taxonomy Id: 83449
Other names: C. ferrugineus, DSM 14716, JCM 12624, Polyangium ferrugineum, strain Cb fe18, strain Windsor M-203
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.