STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirt1Deacetylase sirtuin-type domain-containing protein. (722 aa)    
Predicted Functional Partners:
Tp53.L
P53 domain-containing protein.
    
 0.994
foxo3
Fork-head domain-containing protein.
    
 0.990
Foxo3.L
Fork-head domain-containing protein.
    
 0.988
nadsyn1
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.956
nampt
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.952
nampt-2
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.952
Sirt7.L
Deacetylase sirtuin-type domain-containing protein.
  
 
 0.942
Sirt1.L
Deacetylase sirtuin-type domain-containing protein.
  
  
 
0.900
foxo1
Fork-head domain-containing protein.
    
 0.886
foxo1-2
Fork-head domain-containing protein.
    
 0.886
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.