STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
serpinb5-2SERPIN domain-containing protein; Belongs to the serpin family. (379 aa)    
Predicted Functional Partners:
serpinb5
SERPIN domain-containing protein; Belongs to the serpin family.
  
  
 
0.900
Mat2b.L
Methionine adenosyltransferase 2 subunit beta; Regulatory subunit of S-adenosylmethionine synthetase 2, an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates MAT2A catalytic activity by changing its kinetic properties, increasing its affinity for L-methionine.
      
 0.747
Coro1a.L
WD_REPEATS_REGION domain-containing protein.
      
 0.696
F2.L
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.668
f2
Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.
   
 0.668
fbxo22
Uncharacterized protein.
      
 0.625
A0A1L8HD77
SMB domain-containing protein.
   
 0.583
A0A1L8EWL1
Uncharacterized protein.
    
 0.555
A0A1L8FLR1
Uncharacterized protein.
      
 0.533
hipk3
Protein kinase domain-containing protein.
      
 0.529
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.