STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fshbCys_knot domain-containing protein. (134 aa)    
Predicted Functional Partners:
FSHR
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
   
 0.994
fshr
Follicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways.
   
 0.993
cga
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
   
 
 0.963
cga-2
Glycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family.
   
 
 0.963
Gnrhr.L
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
 
 0.933
gnrh1
Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.922
LHCGR
Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
   
 0.909
Fshb.L
Cys_knot domain-containing protein.
  
  
 
0.900
A0A1L8GE59
NTF2 domain-containing protein.
   
 0.886
Fanca.L
Fanconi_A_N domain-containing protein.
   
 0.886
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.