STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atripUncharacterized protein. (801 aa)    
Predicted Functional Partners:
topbp1
Uncharacterized protein.
    
 0.999
Atr.L
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
    
 0.999
Rpa1.L
Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.
    
 0.993
Fancm.L
Uncharacterized protein.
     
 0.992
rad9a
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 
 0.991
fanci
Uncharacterized protein.
     
 0.989
Fanca.L
Fanconi_A_N domain-containing protein.
  
 
 0.987
chek1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.983
chek1-2
Protein kinase domain-containing protein.
    
 0.983
Rad17.L
Uncharacterized protein.
   
 0.982
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.