STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rtn3.LReticulon. (206 aa)    
Predicted Functional Partners:
atl1-2
GB1/RHD3-type G domain-containing protein.
    
 
 0.915
A0A1L8G1T9
GB1/RHD3-type G domain-containing protein.
    
 
 0.914
A0A1L8GJR8
GB1/RHD3-type G domain-containing protein.
    
 
 0.914
atl1
GB1/RHD3-type G domain-containing protein.
    
 
 0.913
atl2
GB1/RHD3-type G domain-containing protein.
    
 
 0.913
A0A1L8H267
Uncharacterized protein.
    
 
 0.903
sec61b
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum.
    
 
 0.881
tmem33
Uncharacterized protein.
    
 
 0.837
tmem33-2
Tmem33-prov protein.
    
 
 0.837
SPAST
Spastin; ATP-dependent microtubule severing protein that specifically recognizes and cuts microtubules that are polyglutamylated. Preferentially recognizes and acts on microtubules decorated with short polyglutamate tails: severing activity increases as the number of glutamates per tubulin rises from one to eight, but decreases beyond this glutamylation threshold. Microtubule severing promotes reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Go [...]
   
 
 0.822
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.