STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem127.SUncharacterized protein. (364 aa)    
Predicted Functional Partners:
Atp6v1d.L
Uncharacterized protein.
      
 0.760
arhgap27
Uncharacterized protein.
      
 0.626
march8
RING-CH-type domain-containing protein.
      
 0.565
march8-2
RING-CH-type domain-containing protein.
      
 0.565
Ret.L
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
      
 0.563
Mpv17.L
Uncharacterized protein; Belongs to the peroxisomal membrane protein PXMP2/4 family.
      
 0.552
Dbnl.L
Uncharacterized protein.
      
 0.533
sdhaf2
Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer.
      
 0.519
mapk10-2
Mitogen-activated protein kinase.
      
 0.519
Csnk1d.S
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
  
 0.509
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.