STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1L8H7S1Fibronectin type-III domain-containing protein. (148 aa)    
Predicted Functional Partners:
A0A1L8G5M3
Uncharacterized protein.
   
 0.641
itsn2
Uncharacterized protein.
   
 0.641
Efnb2.S
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.589
efnb1
Ephrin-B1 (EPH family ligand); Belongs to the ephrin family.
   
 0.589
efnb2
Efnb2a protein; Belongs to the ephrin family.
   
 0.589
Efna5.S
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.512
Efna5.L
Ephrin RBD domain-containing protein; Belongs to the ephrin family.
   
 0.512
Itsn1.S
Uncharacterized protein.
    
 0.472
Itsn1.L
Uncharacterized protein.
    
 0.472
itsn1
Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for cdc42, and thereby stimulates actin nucleation mediated by wasl and the arp2/3 complex (By similarity). Involved in endocytosis of activated egfr, and probably also other growth factor receptors (By similarity).
    
 0.472
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.