STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Aaed1.SUncharacterized protein. (228 aa)    
Predicted Functional Partners:
prxl2a
Uncharacterized protein.
      
 0.919
Selenot.S
Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily.
      
 0.859
Selenot.L
Selenoprotein T; Belongs to the SelWTH family. Selenoprotein T subfamily.
      
 0.859
Selenon.S
EF-hand domain-containing protein.
      
 0.674
Selenon.L
EF-hand domain-containing protein.
      
 0.674
trip12
Uncharacterized protein.
      
 0.525
trip12-2
Uncharacterized protein.
      
 0.525
A0A310U4X2
Uncharacterized protein.
      
 0.525
Mrps27.L
Uncharacterized protein.
      
 0.457
fbxl17
F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome (By similarity). The ability of the SCF(FBXL17) complex to eliminate co [...]
      
 0.454
Your Current Organism:
Xenopus laevis
NCBI taxonomy Id: 8355
Other names: African clawed frog, Bufo laevis, X. laevis, clawed frog, common platanna, platanna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.