STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RASGRP2RAS guanyl releasing protein 2. (581 aa)    
Predicted Functional Partners:
mras
Thrombospondin 3.
    
 0.795
rras
Transducin like enhancer of split 1.
    
 0.753
nras
Novel gene of the neuroblastoma RAS viral (V-ras) oncogene homolog family.
    
 0.736
hras
Chloride channel accessory 1 gene 1.
    
 0.736
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
    
 0.736
rap1b
Ras-related protein Rap-1b; Probable GTP-binding protein that possesses GTPase activity. May play a role in endothelial cell polarity and endothelial barrier function (By similarity); Belongs to the small GTPase superfamily. Ras family.
    
 
 0.672
rap1a
Aldehyde dehydrogenase 1 family member A3.
    
 
 0.672
CACNA1A
Calcium voltage-gated channel subunit alpha1 A.
   
 
  0.652
Cacna1b
Ion_trans domain-containing protein.
   
 
  0.652
CACNA1C
Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family.
   
 
  0.652
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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