STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL18R1Interleukin 18 receptor 1. (395 aa)    
Predicted Functional Partners:
LOC100496716
Uncharacterized protein.
   
 
 0.961
il1rap
Uncharacterized protein.
    
 
0.614
MFSD9
Major facilitator superfamily domain containing 9.
      
 0.593
hesx1
Homeobox expressed in ES cells 1; Regulates the earliest stages of development of the anterior neural plate. Plays a role in forebrain development by inhibiting the expression of otx2 and pax6 in the rostral region of the anterior neural plate. Necessary for both neural differentiation and neural patterning. Controls Spemann organizer development. May act as a transcriptional repressor (By similarity).
      
 0.525
sigirr
Single Ig and TIR domain containing.
   
  
0.486
il1b
Interleukin-1; Belongs to the IL-1 family.
   
  
 0.470
sgf29
Pseudouridine synthase like 1.
      
 0.467
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.