STRINGSTRING
egfl7 protein (Xenopus tropicalis) - STRING interaction network
"egfl7" - EGF-like-domain, multiple 7 in Xenopus tropicalis
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
egfl7EGF-like-domain, multiple 7 (279 aa)    
Predicted Functional Partners:
spred1
Sprouty-related, EVH1 domain containing 1 (415 aa)
       
 
  0.816
casz1
Castor zinc finger 1 (1632 aa)
     
   
  0.806
pik3r2
Phosphoinositide-3-kinase, regulatory subunit 2 (beta) (715 aa)
           
  0.787
kbtbd3
Kelch repeat and BTB (POZ) domain containing 3 (608 aa)
           
  0.654
egf
Uncharacterized protein; Epidermal growth factor (1053 aa)
       
 
  0.633
MEGF6
Multiple EGF-like-domains 6 (1117 aa)
     
 
  0.557
cldn5
Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (216 aa)
     
   
  0.541
chmp2a
Charged multivesicular body protein 2a; Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids (By similarity) (220 aa)
           
  0.515
neurl1b
Neuralized E3 ubiquitin protein ligase 1B; Neuralized homolog 1B (551 aa)
       
 
  0.506
zswim4
Zinc finger, SWIM-type containing 4 (1100 aa)
           
  0.491
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. (Silurana) tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, Xenopus tropicalis, western clawed frog
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