STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yaf2RanBP2-type domain-containing protein. (180 aa)    
Predicted Functional Partners:
FGA
Fibrinogen alpha chain.
     
  0.750
kdm2a
Lysine-specific demethylase 2A; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the c [...]
    
 
 0.712
LOC101730971
Rho GTPase activating protein 25.
    
 
 0.712
KDM2B
Uncharacterized protein.
    
 
 0.712
fbxl19
GULP PTB domain containing engulfment adaptor 1.
    
 
 0.712
L3MBTL2
L3MBTL histone methyl-lysine binding protein 2.
    
 0.710
rnf2
Ring finger protein 2.
    
 
 0.708
ring1
RING-type domain-containing protein.
    
 
 0.708
PCGF5
Polycomb group ring finger 5.
    
 
 0.645
AUTS2
Activator of transcription and developmental regulator AUTS2.
    
 
 0.641
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.