STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
paaf1WD_REPEATS_REGION domain-containing protein. (406 aa)    
Predicted Functional Partners:
psmd10
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10.
    
 
 0.678
psmc5
Microtubule associated protein 7; Belongs to the AAA ATPase family.
    
 
 0.678
psmc2
Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha; Belongs to the AAA ATPase family.
    
 
 0.655
psmc4
Proteasome (Prosome, macropain) 26S subunit, ATPase, 4; Belongs to the AAA ATPase family.
    
 
 0.621
psmc3
CD248 molecule; Belongs to the AAA ATPase family.
    
 
 0.589
psmd7
Nicotinamide nucleotide transhydrogenase.
    
 
 0.586
psmd14
Prokineticin receptor 2.
    
 
 0.574
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
    
 
 0.543
psmd13
PHD finger protein 12.
    
 
 0.540
psmc1
Proteasome (Prosome, macropain) 26S subunit, ATPase, 1; Belongs to the AAA ATPase family.
    
 
 0.513
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.