STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEMFNuclear export mediator factor. (1058 aa)    
Predicted Functional Partners:
ltn1
E3 ubiquitin-protein ligase listerin; E3 ubiquitin-protein ligase. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Ubiquitination leads to vcp/p97 recruitment for extraction and degradation of the incomplete translation product; Belongs to the LTN1 family.
    
 
 0.966
rpl11
Uncharacterized protein; Belongs to the universal ribosomal protein uL5 family.
   
 
 0.866
rpl8
60S ribosomal protein L8; Component of the large ribosomal subunit.
    
   0.858
rpl5
Sideroflexin 3.
    
   0.858
rpl23
Uncharacterized protein.
   
   0.854
rpl23a
Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family.
    
   0.853
rpl35
60S ribosomal protein L35; Component of the large ribosomal subunit. Belongs to the universal ribosomal protein uL29 family.
    
   0.838
tcf25
Transmembrane protein 161B.
    
 
 0.829
mcm10
Protein MCM10 homolog; Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication (By similarity).
     
  0.800
gdnf-2
KN motif and ankyrin repeat domains 4.
     
  0.800
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.