node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSXETP00000001570 | ccdc38 | ENSXETP00000001570 | ENSXETP00000046747 | Mediator of RNA polymerase II transcription subunit 8. | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | 0.800 |
ENSXETP00000001570 | cdk6 | ENSXETP00000001570 | ENSXETP00000017041 | Mediator of RNA polymerase II transcription subunit 8. | Epidermal growth factor receptor pathway substrate 15; Belongs to the protein kinase superfamily. | 0.540 |
ENSXETP00000001570 | ddc | ENSXETP00000001570 | ENSXETP00000000617 | Mediator of RNA polymerase II transcription subunit 8. | Uncharacterized protein. | 0.800 |
ENSXETP00000001570 | epha3 | ENSXETP00000001570 | ENSXETP00000003242 | Mediator of RNA polymerase II transcription subunit 8. | Transcription factor E2F8. | 0.804 |
ENSXETP00000001570 | fra10ac1 | ENSXETP00000001570 | ENSXETP00000046356 | Mediator of RNA polymerase II transcription subunit 8. | Uncharacterized protein. | 0.800 |
ENSXETP00000001570 | med10 | ENSXETP00000001570 | ENSXETP00000014942 | Mediator of RNA polymerase II transcription subunit 8. | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.800 |
ENSXETP00000001570 | med16 | ENSXETP00000001570 | ENSXETP00000038276 | Mediator of RNA polymerase II transcription subunit 8. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.540 |
ENSXETP00000001570 | med17 | ENSXETP00000001570 | ENSXETP00000027764 | Mediator of RNA polymerase II transcription subunit 8. | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.800 |
ENSXETP00000001570 | med27 | ENSXETP00000001570 | ENSXETP00000030650 | Mediator of RNA polymerase II transcription subunit 8. | Mediator of RNA polymerase II transcription subunit 27; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.540 |
ENSXETP00000001570 | wnk2 | ENSXETP00000001570 | ENSXETP00000001056 | Mediator of RNA polymerase II transcription subunit 8. | Guanine nucleotide binding protein (G protein), alpha 13. | 0.804 |
ccdc38 | ENSXETP00000001570 | ENSXETP00000046747 | ENSXETP00000001570 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Mediator of RNA polymerase II transcription subunit 8. | 0.800 |
ccdc38 | ddc | ENSXETP00000046747 | ENSXETP00000000617 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Uncharacterized protein. | 0.802 |
ccdc38 | epha3 | ENSXETP00000046747 | ENSXETP00000003242 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Transcription factor E2F8. | 0.802 |
ccdc38 | fra10ac1 | ENSXETP00000046747 | ENSXETP00000046356 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Uncharacterized protein. | 0.800 |
ccdc38 | med10 | ENSXETP00000046747 | ENSXETP00000014942 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.800 |
ccdc38 | med16 | ENSXETP00000046747 | ENSXETP00000038276 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.802 |
ccdc38 | med17 | ENSXETP00000046747 | ENSXETP00000027764 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.800 |
ccdc38 | med27 | ENSXETP00000046747 | ENSXETP00000030650 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Mediator of RNA polymerase II transcription subunit 27; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). | 0.800 |
ccdc38 | wnk2 | ENSXETP00000046747 | ENSXETP00000001056 | Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. | Guanine nucleotide binding protein (G protein), alpha 13. | 0.802 |
cdk6 | ENSXETP00000001570 | ENSXETP00000017041 | ENSXETP00000001570 | Epidermal growth factor receptor pathway substrate 15; Belongs to the protein kinase superfamily. | Mediator of RNA polymerase II transcription subunit 8. | 0.540 |