STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
itsn1Thiamin pyrophosphokinase 1. (1710 aa)    
Predicted Functional Partners:
cdc42
Uncharacterized protein.
    
 
 0.888
ap2m1
AP-2 complex subunit mu; Component of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. AP50 is a subunit of the plasma membrane adaptor. The complex binds polyphosphoinositide- containing lipids (By similarity).
    
 
 0.868
ap2b1
AP complex subunit beta.
    
 
 0.845
ap1b1
AP complex subunit beta.
    
 
 0.845
AP4B1
AP complex subunit beta; Belongs to the adaptor complexes large subunit family.
    
 
 0.845
ap2s1
AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.
   
 
 0.837
rhof
Protein phosphatase 3, catalytic subunit, gamma isozyme.
    
 
 0.806
rnd1
N-lysine methyltransferase KMT5A.
    
 
 0.806
rac2
Ras-related C3 botulinum toxin substrate 2 (Rho family, small GTP binding protein Rac2).
    
 
 0.806
rhoa.2
Nuclear receptor binding SET domain protein 3.
    
 
 0.806
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.