STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERPINH1Serpin family H member 1; Belongs to the serpin family. (450 aa)    
Predicted Functional Partners:
tmprss2.5
Transformer 2 alpha homolog.
    
  0.706
fkbp10
Peptidylprolyl isomerase.
   
 
 0.703
dnajc3
DnaJ (Hsp40) homolog, subfamily C, member 3.
     
 0.617
faf2
FAS-associated factor 2; Plays an important role in endoplasmic reticulum associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Involved in inhibition of lipid droplet degradation.
    
  0.542
PPIC
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 
 0.522
nudt9
Nudix hydrolase domain-containing protein.
   
 
  0.504
serpinb11
Methyltransferase like 25; Belongs to the serpin family.
  
 
0.494
fkbp9
Peptidylprolyl isomerase.
   
 
 0.473
emid1
EMI domain-containing protein.
    
 
 0.471
cd248
Iroquois-class homeodomain protein irx-4.
   
  
 0.462
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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