STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sclySelenocysteine lyase; Catalyzes the decomposition of L-selenocysteine to L-alanine and elemental selenium. (440 aa)    
Predicted Functional Partners:
iscu
NifU-like N-terminal domain containing; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.
 
 0.998
FXN
Frataxin.
   
 0.980
sephs1
Selenide, water dikinase 1; Synthesizes selenophosphate from selenide and ATP.
    
 0.972
nfu1
Family with sequence similarity 193 member B.
  
 0.960
tstd3
Rhodanese domain-containing protein.
   
 0.917
txnrd1
N-myristoyltransferase 1; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.915
txnrd3
Glutaredoxin domain-containing protein; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.915
MOCOS
Molybdenum cofactor sulfurase; Sulfurates the molybdenum cofactor. Sulfation of molybdenum is essential for xanthine dehydrogenase (XDH) and aldehyde oxidase (ADO) enzymes in which molybdenum cofactor is liganded by 1 oxygen and 1 sulfur atom in active form.
    
 0.911
lyrm4
Whirlin; Belongs to the complex I LYR family.
   
 
 0.904
suox
Cytochrome b5 heme-binding domain-containing protein.
   
  
 0.797
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.