| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HNRNPM | SRRT | ENSXETP00000045339 | ENSXETP00000010567 | Heterogeneous nuclear ribonucleoprotein M. | Uncharacterized protein. | 0.709 |
| HNRNPM | alyref | ENSXETP00000045339 | ENSXETP00000001902 | Heterogeneous nuclear ribonucleoprotein M. | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | 0.598 |
| HNRNPM | ncbp1 | ENSXETP00000045339 | ENSXETP00000026225 | Heterogeneous nuclear ribonucleoprotein M. | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U sn [...] | 0.488 |
| HNRNPM | ncbp2 | ENSXETP00000045339 | ENSXETP00000038663 | Heterogeneous nuclear ribonucleoprotein M. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.465 |
| HNRNPM | u2af2 | ENSXETP00000045339 | ENSXETP00000032374 | Heterogeneous nuclear ribonucleoprotein M. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.632 |
| MTREX | SRRT | ENSXETP00000037676 | ENSXETP00000010567 | Mtr4 exosome RNA helicase. | Uncharacterized protein. | 0.672 |
| MTREX | alyref | ENSXETP00000037676 | ENSXETP00000001902 | Mtr4 exosome RNA helicase. | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | 0.600 |
| MTREX | drosha | ENSXETP00000037676 | ENSXETP00000004978 | Mtr4 exosome RNA helicase. | Kruppel-like factor 8. | 0.406 |
| MTREX | ncbp1 | ENSXETP00000037676 | ENSXETP00000026225 | Mtr4 exosome RNA helicase. | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U sn [...] | 0.828 |
| MTREX | ncbp2 | ENSXETP00000037676 | ENSXETP00000038663 | Mtr4 exosome RNA helicase. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.789 |
| MTREX | zfc3h1 | ENSXETP00000037676 | ENSXETP00000028322 | Mtr4 exosome RNA helicase. | NFU1 iron-sulfur cluster scaffold. | 0.955 |
| SRRT | HNRNPM | ENSXETP00000010567 | ENSXETP00000045339 | Uncharacterized protein. | Heterogeneous nuclear ribonucleoprotein M. | 0.709 |
| SRRT | MTREX | ENSXETP00000010567 | ENSXETP00000037676 | Uncharacterized protein. | Mtr4 exosome RNA helicase. | 0.672 |
| SRRT | alyref | ENSXETP00000010567 | ENSXETP00000001902 | Uncharacterized protein. | THO complex subunit 4; Export adapter involved in nuclear export of spliced and unspliced mRNA. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NFX1 pathway). Component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap- dependent manner to a regio [...] | 0.687 |
| SRRT | dicer1 | ENSXETP00000010567 | ENSXETP00000047771 | Uncharacterized protein. | Endoribonuclease Dicer; Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, al [...] | 0.718 |
| SRRT | drosha | ENSXETP00000010567 | ENSXETP00000004978 | Uncharacterized protein. | Kruppel-like factor 8. | 0.680 |
| SRRT | ncbp1 | ENSXETP00000010567 | ENSXETP00000026225 | Uncharacterized protein. | Nuclear cap-binding protein subunit 1; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5'-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5'-end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U sn [...] | 0.974 |
| SRRT | ncbp2 | ENSXETP00000010567 | ENSXETP00000038663 | Uncharacterized protein. | Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] | 0.968 |
| SRRT | phax | ENSXETP00000010567 | ENSXETP00000046790 | Uncharacterized protein. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.713 |
| SRRT | u2af2 | ENSXETP00000010567 | ENSXETP00000032374 | Uncharacterized protein. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.608 |
STRING v12.5 is now available!
