STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RAD21RAD21 cohesin complex component. (631 aa)    
Predicted Functional Partners:
smc3
Structural maintenance of chromosomes protein.
   
 
 0.997
NIPBL
Nipped-B protein.
   
 
 0.996
smc1a
Structural maintenance of chromosomes protein.
   
 0.995
stag1-2
Solute carrier family 16 member 1.
   
 0.976
stag1
SCD domain-containing protein.
   
 0.969
plk1
Serine/threonine-protein kinase PLK1; Plays multiple essential roles during mitosis. Phosphorylates the N-terminal domain of cdc25, which leads to cyclin b-cdc2 activation and mitotic entry. Also required for organization of bipolar spindles, and for exit from mitosis. Phosphorylates tpx2 (By similarity).
   
 0.960
smc1b
Structural maintenance of chromosomes protein.
   
 
 0.945
PDS5A
PDS5 cohesin associated factor A.
   
 
 0.937
pds5b
Uncharacterized protein.
   
 
 0.931
ctcf
Uncharacterized protein.
   
 
 0.914
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.