STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tph1Trace amine associated receptor 2 (gene/pseudogene). (494 aa)    
Predicted Functional Partners:
pcbd1
4a-hydroxytetrahydrobiopterin dehydratase.
  
 0.974
pcbd2
Dihydrolipoamide dehydrogenase.
  
 0.974
ddc
Uncharacterized protein.
   
 0.964
spr
Sepiapterin reductase; Catalyzes the final one or two reductions in tetra- hydrobiopterin biosynthesis to form 5,6,7,8-tetrahydrobiopterin.
   
 
 0.944
qdpr
Interferon-related developmental regulator 2.
    
 0.936
tdo2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
  
 
 0.929
TPH2
Tryptophan hydroxylase 2.
  
 
 
0.924
dhfr
DHFR domain-containing protein.
     
 0.904
LOC100496394
Amine oxidase.
     
 0.904
dhfr-2
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.904
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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