STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mlh1Mitochondrial ribosomal protein L1. (758 aa)    
Predicted Functional Partners:
pms2
Peripherin 2 (retinal degeneration, slow).
    
0.999
brip1
PH domain and leucine rich repeat protein phosphatase 2.
   
 0.992
mlh3
Uncharacterized protein.
    
 
0.991
MSH2
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 
 0.989
MSH6
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
 
 
 0.986
FAN1
Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family.
   
 0.982
MSH3
MutS homolog 3.
 
 
 0.974
pms1
Collagen alpha-1(II) chain.
  
 
 
0.968
exo1
Ubiquitin-fold modifier conjugating enzyme 1.
   
 
 0.968
blm
Uncharacterized protein.
  
 
 0.965
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.