STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
snx5Sorting nexin; Involved in several stages of intracellular trafficking. (406 aa)    
Predicted Functional Partners:
snx6
Sorting nexin; Involved in several stages of intracellular trafficking.
  
  
 
0.901
snx3
Sorting nexin 12.
   
 
 0.769
banf1
Prostaglandin E receptor 3.
      
 0.717
SNX1
Sorting nexin 1.
   
 
0.717
SNX2
Sorting nexin 2.
   
 
0.716
vps29
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. Retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) (By similarity). Acts also as component of the retriever complex. The retriever complex is an heterotrimeric complex related to retromer cargo-selective com [...]
    
 
 0.671
st6gal1
Mastermind like domain containing 1; Belongs to the glycosyltransferase 29 family.
     
  0.540
SNX8
Sorting nexin 8.
   
 
 0.518
snx30
Sorting nexin-30; May be involved in several stages of intracellular trafficking.
   
 
0.499
snx7
Sorting nexin 7.
   
 
0.499
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.