STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cd38Fc receptor, IgG, high affinity I. (300 aa)    
Predicted Functional Partners:
nmnat1
Nicotinamide-nucleotide adenylyltransferase.
     
 0.925
nampt
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
     
 0.925
SIRT3
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.914
pnp
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
   
 
 0.913
nmnat2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate (By similarity). Belongs to the eukaryotic NMN adenylyltransferase family.
     
 0.912
nadk
Uncharacterized protein.
     
 0.911
sirt3.2
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.911
sirt6
Sirtuin (Silent mating type information regulation 2 homolog) 6.
     
 0.906
sirt5
NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo.
     
 0.906
SIRT2
NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.
     
 0.906
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.