Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc45a33-hydroxyacyl-CoA dehydratase 2. (547 aa)    
Predicted Functional Partners:
ELK4
ETS transcription factor ELK4.
      
 0.688
acpp
Transmembrane protein 205; Belongs to the histidine acid phosphatase family.
      
 0.669
phax
Enhancer of zeste 1 polycomb repressive complex 2 subunit.
    
   0.627
etv1
ETS domain-containing protein.
      
 0.619
JAZF1
JAZF zinc finger 1.
      
 0.618
pm20d1
N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
      
 0.614
SLC6A20
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.604
nucks1
Nuclear casein kinase and cyclin-dependent kinase substrate 1.
      
 0.601
rab29
LOC100135159 protein.
      
 0.585
steap2
Exocyst complex component 3-like 1.
      
 0.583
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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