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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc45a33-hydroxyacyl-CoA dehydratase 2. (547 aa)    
Predicted Functional Partners:
acpp
Transmembrane protein 205; Belongs to the histidine acid phosphatase family.
      
 0.588
etv1
ETS domain-containing protein.
   
  
 0.571
SLC6A20
Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
      
 0.501
ELK4
ETS transcription factor ELK4.
 
 
  
 0.483
pm20d1
N-fatty-acyl-amino acid synthase/hydrolase PM20D1; Bidirectional N-fatty-acyl amino acid synthase/hydrolase that regulates the production of N-fatty-acyl amino acids. These metabolites are endogenous chemical uncouplers of mitochondrial respiration. In an UCP1-independent manner, maybe through interaction with mitochondrial transporters, they promote proton leakage into the mitochondrial matrix. Thereby, this secreted protein may indirectly regulate the bodily dissipation of chemical energy as heat through thermogenic respiration.
      
 0.418
nucks1
Nuclear casein kinase and cyclin-dependent kinase substrate 1.
      
 0.404
HAPLN2
Hyaluronan and proteoglycan link protein 2.
   
  
 0.402
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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