STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cand1Nodal homolog 5. (1285 aa)    
Predicted Functional Partners:
kpna2
Importin subunit alpha; Belongs to the importin alpha family.
   
 
  0.901
cul1
Complexin 1; Belongs to the cullin family.
   
 
 0.878
RBX1
Ring-box 1.
    
 
 0.834
cul3
Cullin-3; Probable core component of cullin-based SCF-like E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit (By similarity). Involved in ER- Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division (By similarity). May play a role in the regulation of mittotic entry via ubiquitinati [...]
   
 
 0.762
CUL2
Cullin 2; Belongs to the cullin family.
    
 
 0.733
ccna1
DEP domain containing 1B; Belongs to the cyclin family.
     
 0.717
CNTN1
Contactin 1.
     
  0.700
LEPROTL1
Leptin receptor overlapping transcript like 1.
     
  0.700
brd1
Bromodomain-containing 1.
   
 
  0.700
fam98a-2
Calpain 15.
     
  0.700
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.