STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lrrc49RNA binding protein with multiple splicing 2. (763 aa)    
Predicted Functional Partners:
TTLL1
Tubulin tyrosine ligase like 1.
    
 
 0.678
tpgs1
SLU7 homolog, splicing factor.
    
 
 0.670
mst1r
Uncharacterized protein.
   
 
 0.627
ppp1cc
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit; Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Promotes nuclear envelope reassembly by targeting nuclear membrane vesicles to chromatin at the end of mitosis. Acts by dephosphorylating membrane proteins such as lamin B receptor (lbr) to regulate the binding of membrane proteins to chromatin (By similarity); Belongs to the PPP phosphatase family. PP-1 subfamily.
   
 0.623
tpgs2
SMI1_KNR4 domain-containing protein.
    
 
 0.614
bbox1-2
Cysteine-rich secretory protein 2; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.580
adgrl1
DEAH-box helicase 36; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.580
adgrl2
Hemopexin; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.580
ppp1r3b
Protein phosphatase 1 regulatory subunit 3B; Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown (By similarity).
    
 0.556
ppp1r3c.2
Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown (By similarity).
    
 0.556
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.