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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
INPPL1Inositol polyphosphate phosphatase like 1. (925 aa)    
Predicted Functional Partners:
tns1
ADAM metallopeptidase with thrombospondin type 1 motif 12.
   
 
 0.599
SHC1
SHC adaptor protein 1.
    
 
 0.581
shc3
Optic atrophy 1 (autosomal dominant).
    
 
 0.581
apba1
Acyl-CoA synthetase short chain family member 1.
      
 0.578
NTNG1
Netrin G1.
     
  0.567
tnrc6c
Serine/threonine-protein phosphatase 4 regulatory subunit 3.
   
 
  0.550
ntng1
Uncharacterized protein.
   
 
  0.550
polk
SEC31 homolog A, COPII coat complex component.
     
  0.540
GCC2
GRIP and coiled-coil domain containing 2.
     
  0.540
PPP1R13B
Protein phosphatase 1 regulatory subunit 13B.
     
  0.540
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.