Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
scnn1aClaudin 16; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (632 aa)    
Predicted Functional Partners:
scnn1b
Sodium channel, nonvoltage-gated 1, beta; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
0.871
scnn1g
Cadherin 12, type 2 (N-cadherin 2); Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family.
  
0.841
scn2b
Period circadian regulator 1.
     
 0.621
nedd4
E3 ubiquitin-protein ligase.
    
 
 0.596
nedd4l
Nitric oxide synthase 2.
    
 
 0.596
SCN1B
Sodium voltage-gated channel beta subunit 1.
     
 0.504
wwp1
E3 ubiquitin-protein ligase.
    
  0.502
nup58
Uncharacterized protein.
     
  0.500
INHBA
Inhibin subunit beta A.
      
 0.488
srsf7-2
Proline-rich coiled-coil 2C.
      
 0.459
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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