STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arl14eplChromosome 15 open reading frame 41. (155 aa)    
Predicted Functional Partners:
ATF7IP
Activating transcription factor 7 interacting protein.
    
 
 0.855
setdb1
Uncharacterized protein.
    
 
 0.831
setdb2
Histone-lysine N-methyltransferase SETDB2; Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis (By similarity); Belongs to the class V-like SAM-binding meth [...]
    
 
 0.831
atf7ip2
Splicing factor 3b subunit 6.
    
 
 0.753
oscp1
Uncharacterized protein.
      
 0.576
pdrg1
Similar to dJ310O13.3 (Novel protein).
      
 0.573
suox
Cytochrome b5 heme-binding domain-containing protein.
      
 0.563
tmem65
Uncharacterized protein.
   
  
 0.528
naa50
N-alpha-acetyltransferase 50; N-alpha-acetyltransferase that acetylates the N-terminus of proteins that retain their initiating methionine. Has a broad substrate specificity: able to acetylate the initiator methionine of most peptides, except for those with a proline in second position. Also displays N-epsilon-acetyltransferase activity by mediating acetylation of the side chain of specific lysines on proteins. The relevance of N- epsilon-acetyltransferase activity is however unclear. Required for sister chromatid cohesion during mitosis by promoting binding of CDCA5/sororin to cohesin [...]
      
 0.505
nhlrc2
Zinc finger and BTB domain containing 47.
      
 0.471
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.