STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
slc2a2DnaJ heat shock protein family (Hsp40) member C28; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (541 aa)    
Predicted Functional Partners:
ensa
Alpha-endosulfine; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. When phosphorylated at Ser-67 during mitosis, specifically interacts with ppp2r2d (PR55-delta) and inhibits its activity, leading to inactivation of PP2A, an essential condition to keep cyclin-B1-CDK1 activity high during M phase (By similarity).
   
 
  0.754
TREH
Trehalase.
   
  
 0.692
serpinc1
Thioredoxin like 4B; Belongs to the serpin family.
   
  
 0.623
apob
Probable ATP-dependent RNA helicase ddx6.
   
 
 0.565
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
  
 0.548
slc22a20p.1
MFS domain-containing protein.
  
 
 0.537
ggcx-2
Gamma-glutamyl carboxylase.
  
 
 0.506
serpine2
SERPIN domain-containing protein; Belongs to the serpin family.
      
 0.504
slc22a8
MFS domain-containing protein.
  
 
 0.500
ENSXETP00000019585
MFS domain-containing protein.
  
 
 0.499
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.