STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRDM13PR/SET domain 13. (632 aa)    
Predicted Functional Partners:
bhlhe22
Class E basic helix-loop-helix protein 22; May act as a transcriptional repressor.
      
 0.565
pole
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
   
  
 0.519
samd7
Nucleoporin 88kDa.
      
 0.490
PTF1A
Pancreas associated transcription factor 1a.
   
 
 0.467
hnf4b
PR domain containing 12.
    
 
 0.460
DBX2
Developing brain homeobox 2.
    
 
 0.460
rcvrn.1
F-box and WD repeat domain containing 7.
    
 
 0.454
rcvrn.2
Collagen type XVIII alpha 1.
    
 
 0.454
hnmt
Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family.
      
 0.412
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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