Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mpp7MAGUK p55 subfamily member 7; Acts as an important adapter that promotes epithelial cell polarity and tight junction formation. Involved in the assembly of protein complexes at sites of cell-cell contact (By similarity). Belongs to the MAGUK family. (576 aa)    
Predicted Functional Partners:
UCHL5
Ubiquitin carboxyl-terminal hydrolase.
    
 
 0.776
eogt
EGF domain-specific O-linked N-acetylglucosamine transferase; Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains. Belongs to the glycosyltransferase 61 family.
   
 
 0.739
CEP290
Centrosomal protein 290.
    
 
 0.695
snap25
Synaptosomal-associated protein; Belongs to the SNAP-25 family.
   
  
 0.671
pard6g
Par-6 partitioning defective 6 homolog gamma (C. elegans).
   
 
 0.641
pard6b
Uncharacterized protein.
   
 
 0.641
CD34
Uncharacterized protein.
      
 0.637
pard3
Potassium channel, voltage-gated shaker-related subfamily A, member 5.
   
 
 0.626
pard3b
Zinc finger protein 532.
   
 
 0.626
idh2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
     
 0.623
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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