STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (2276 aa)    
Predicted Functional Partners:
CNTN1
Contactin 1.
   
 
 0.911
ptn
Glycine receptor alpha 3.
   
 
 0.902
BCAN
Brevican.
   
 
 0.745
ppid-2
Peptidylprolyl isomerase D (cyclophilin D).
      
 0.625
mdk
Midkine; Secreted protein that functions as cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non- proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration (By similarity). Inhibits mesoderm formation and promotes neural formation during development. Plays a role in development of the neuromuscular junction (NMJ). [...]
    
 
 0.615
apob
Probable ATP-dependent RNA helicase ddx6.
    
 
 0.599
CENPF
Centromere protein F.
      
 0.577
cntn2
Polymerase (RNA) II subunit I.
   
 
 0.571
PDZD8
PDZ domain containing 8.
      
 0.549
map3k4
EPH receptor B1.
   
 
 0.542
Your Current Organism:
Xenopus tropicalis
NCBI taxonomy Id: 8364
Other names: Silurana tropicalis, X. tropicalis, Xenopus (Silurana) tropicalis, Xenopus laevis tropicalis, tropical clawed frog, western clawed frog
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.