Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
degQ_1Serine endoprotease DegQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (454 aa)    
Predicted Functional Partners:
ompA
Hypothetical protein; OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
    
 
 0.860
rseA
Anti-sigma factor; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading [...]
  
 
 0.827
degS_3
Outer membrane-stress sensor serine endopeptidase DegS; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.606
fkpA
Peptidylprolyl isomerase; Rotamase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.598
rseP_3
Zinc metallopeptidase RseP; Catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.556
pspC
Phage shock protein C; With PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.553
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
  
 0.532
yhcB
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.513
yaeT_1
Part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.508
rpsI
30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uS9 family.
   
   0.474
Your Current Organism:
Leclercia adecarboxylata
NCBI taxonomy Id: 83655
Other names: ATCC 23216, CIP 82.92, DSM 5077, Escherichia adecarboxylata, L. adecarboxylata, LMG 2803, LMG:2803, Leclercia sp. LK24, NBRC 102595, NCTC 13032
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