Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ycdT_3Diguanylate cyclase; Catalyzes the formation of cyclic di-3',5'-guanylate from guanosine triphosphate; involved in the regulation of cellulose biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)    
Predicted Functional Partners:
yhjK
Biofilm formation regulator HmsP; HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.848
yjcC_1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.825
yfgF_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.824
cph2_4
c-di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.819
ycgG_3
Antibiotic ABC transporter substrate-binding protein; With YejBEF is involved in resistance to microcin C; frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.818
yjcC_3
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.799
yfgF_3
c-di-GMP phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.779
yhjH
Cyclic-guanylate-specific phosphodiesterase; In Escherichia coli this protein is involved in flagellar function; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.775
ycgF_2
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.751
ycgF_1
Diguanylate phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.727
Your Current Organism:
Leclercia adecarboxylata
NCBI taxonomy Id: 83655
Other names: ATCC 23216, CIP 82.92, DSM 5077, Escherichia adecarboxylata, L. adecarboxylata, LMG 2803, LMG:2803, Leclercia sp. LK24, NBRC 102595, NCTC 13032
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