STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csiR_1Regulator of gab gene expression; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)    
Predicted Functional Partners:
csiD
In Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.837
lhgO_1
Hydroxyglutarate oxidase; Catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.722
ydfH
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.693
mcbR
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.651
gabT
4-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
     
 0.646
gabD-2
NAD-dependent succinate-semialdehyde dehydrogenase; Catalyzes the formation of succinate from succinate semialdehyde; NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.597
nadR_2
Transcriptional regulator; Catalyzes the formation of NAD(+) from nicotinamide ribonucleotide; catalyzes the formation of nicotinamide mononucleotide from nicotinamide riboside; also has a regulatory function; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.586
pdhR_1
Transcriptional regulator; Represses the lctPRD operon; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.564
pdhR
Transcriptional regulator PdhR; Activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.511
pdhR_4
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.492
Your Current Organism:
Leclercia adecarboxylata
NCBI taxonomy Id: 83655
Other names: ATCC 23216, CIP 82.92, DSM 5077, Escherichia adecarboxylata, L. adecarboxylata, LMG 2803, LMG:2803, Leclercia sp. LK24, NBRC 102595, NCTC 13032
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