node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARD07064.1 | ampC | B1745_05230 | B1745_04315 | Multidrug transporter subunit MdtG; Confers resistance to fosfomycin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology. | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
ampC | ARD07064.1 | B1745_04315 | B1745_05230 | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Multidrug transporter subunit MdtG; Confers resistance to fosfomycin and deoxycholate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.459 |
ampC | mprF | B1745_04315 | B1745_05785 | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | 0.408 |
ampC | murQ | B1745_04315 | B1745_07225 | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.849 |
ampC | nagZ | B1745_04315 | B1745_05615 | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
ampC | scrA | B1745_04315 | B1745_01765 | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
mprF | ampC | B1745_05785 | B1745_04315 | Hypothetical protein; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms. | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.408 |
murQ | ampC | B1745_07225 | B1745_04315 | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.849 |
murQ | nagZ | B1745_07225 | B1745_05615 | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.419 |
murQ | scrA | B1745_07225 | B1745_01765 | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.747 |
nagZ | ampC | B1745_05615 | B1745_04315 | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
nagZ | murQ | B1745_05615 | B1745_07225 | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.419 |
nagZ | scrA | B1745_05615 | B1745_01765 | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.591 |
scrA | ampC | B1745_01765 | B1745_04315 | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
scrA | murQ | B1745_01765 | B1745_07225 | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Permease; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. | 0.747 |
scrA | nagZ | B1745_01765 | B1745_05615 | PTS beta-glucoside transporter subunit EIIBCA; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | beta-N-acetylhexosaminidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.591 |