STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFN05891.1Isocitrate dehydrogenase (NADP). (423 aa)    
Predicted Functional Partners:
SFO03991.1
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.983
SFM95226.1
2-oxoglutarate dehydrogenase E1 component.
   
 
 0.975
SFN23975.1
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.966
SFO03967.1
Aconitase.
  
 
 0.942
SFN56969.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.939
SFO00547.1
Glutamate synthase (NADPH/NADH) large chain.
    
 0.939
SFN40138.1
Fumarate hydratase, class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.920
SFN54813.1
Fumarase, class I, homodimeric; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.920
SFN82764.1
Aconitase.
 
 0.919
sucC
succinyl-CoA synthetase beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
  
 0.906
Your Current Organism:
Formivibrio citricus
NCBI taxonomy Id: 83765
Other names: ATCC 49791, DSM 6150, F. citricus, strain CreCit1
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