node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFN74996.1 | ychF | SAMN05660284_02186 | SAMN05660284_02641 | L-threonine aldolase. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.866 |
argS | guaA | SAMN05660284_02312 | SAMN05660284_01753 | arginyl-tRNA synthetase. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.989 |
argS | lepA | SAMN05660284_02312 | SAMN05660284_00586 | arginyl-tRNA synthetase. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.707 |
argS | metG | SAMN05660284_02312 | SAMN05660284_00869 | arginyl-tRNA synthetase. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.977 |
argS | pheT | SAMN05660284_02312 | SAMN05660284_00817 | arginyl-tRNA synthetase. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.892 |
argS | prfA | SAMN05660284_02312 | SAMN05660284_02692 | arginyl-tRNA synthetase. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.670 |
argS | pyrG | SAMN05660284_02312 | SAMN05660284_01020 | arginyl-tRNA synthetase. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.870 |
argS | ychF | SAMN05660284_02312 | SAMN05660284_02641 | arginyl-tRNA synthetase. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.782 |
guaA | argS | SAMN05660284_01753 | SAMN05660284_02312 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase. | 0.989 |
guaA | lepA | SAMN05660284_01753 | SAMN05660284_00586 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.618 |
guaA | metG | SAMN05660284_01753 | SAMN05660284_00869 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.821 |
guaA | pheT | SAMN05660284_01753 | SAMN05660284_00817 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.932 |
guaA | pth | SAMN05660284_01753 | SAMN05660284_00825 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | peptidyl-tRNA hydrolase, PTH1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.587 |
guaA | pyrG | SAMN05660284_01753 | SAMN05660284_01020 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.987 |
guaA | topA | SAMN05660284_01753 | SAMN05660284_01118 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.590 |
guaA | ychF | SAMN05660284_01753 | SAMN05660284_02641 | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | Hypothetical protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. | 0.760 |
lepA | argS | SAMN05660284_00586 | SAMN05660284_02312 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | arginyl-tRNA synthetase. | 0.707 |
lepA | guaA | SAMN05660284_00586 | SAMN05660284_01753 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.618 |
lepA | metG | SAMN05660284_00586 | SAMN05660284_00869 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.549 |
lepA | pheT | SAMN05660284_00586 | SAMN05660284_00817 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.603 |