node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDG62505.1 | SDG63723.1 | SAMN05660652_00283 | SAMN05660652_00321 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Phosphoserine phosphatase. | 0.920 |
SDG62505.1 | SDG64236.1 | SAMN05660652_00283 | SAMN05660652_00336 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine biosynthesis protein MetW. | 0.614 |
SDG62505.1 | SDG64270.1 | SAMN05660652_00283 | SAMN05660652_00337 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG. | 0.592 |
SDG62505.1 | SDG85854.1 | SAMN05660652_00283 | SAMN05660652_00747 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine dehydrogenase. | 0.968 |
SDG62505.1 | SDG86359.1 | SAMN05660652_00283 | SAMN05660652_00761 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Biotin synthase. | 0.424 |
SDG62505.1 | gcvP | SAMN05660652_00283 | SAMN05660652_00893 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.662 |
SDG62505.1 | metXS | SAMN05660652_00283 | SAMN05660652_00335 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.957 |
SDG63723.1 | SDG62505.1 | SAMN05660652_00321 | SAMN05660652_00283 | Phosphoserine phosphatase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.920 |
SDG63723.1 | SDG64236.1 | SAMN05660652_00321 | SAMN05660652_00336 | Phosphoserine phosphatase. | Methionine biosynthesis protein MetW. | 0.596 |
SDG63723.1 | SDG85854.1 | SAMN05660652_00321 | SAMN05660652_00747 | Phosphoserine phosphatase. | Homoserine dehydrogenase. | 0.904 |
SDG63723.1 | gcvP | SAMN05660652_00321 | SAMN05660652_00893 | Phosphoserine phosphatase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.410 |
SDG63723.1 | metXS | SAMN05660652_00321 | SAMN05660652_00335 | Phosphoserine phosphatase. | Homoserine O-acetyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine. | 0.893 |
SDG64236.1 | SDG62505.1 | SAMN05660652_00336 | SAMN05660652_00283 | Methionine biosynthesis protein MetW. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.614 |
SDG64236.1 | SDG63723.1 | SAMN05660652_00336 | SAMN05660652_00321 | Methionine biosynthesis protein MetW. | Phosphoserine phosphatase. | 0.596 |
SDG64236.1 | SDG64270.1 | SAMN05660652_00336 | SAMN05660652_00337 | Methionine biosynthesis protein MetW. | MFS transporter, PAT family, beta-lactamase induction signal transducer AmpG. | 0.844 |
SDG64236.1 | SDG64299.1 | SAMN05660652_00336 | SAMN05660652_00338 | Methionine biosynthesis protein MetW. | Single-strand selective monofunctional uracil DNA glycosylase. | 0.802 |
SDG64236.1 | SDG85854.1 | SAMN05660652_00336 | SAMN05660652_00747 | Methionine biosynthesis protein MetW. | Homoserine dehydrogenase. | 0.607 |
SDG64236.1 | SDG86359.1 | SAMN05660652_00336 | SAMN05660652_00761 | Methionine biosynthesis protein MetW. | Biotin synthase. | 0.553 |
SDG64236.1 | SDG90265.1 | SAMN05660652_00336 | SAMN05660652_00862 | Methionine biosynthesis protein MetW. | Electron-transferring-flavoprotein dehydrogenase; Accepts electrons from ETF and reduces ubiquinone. | 0.581 |
SDG64236.1 | bioD | SAMN05660652_00336 | SAMN05660652_01190 | Methionine biosynthesis protein MetW. | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.553 |