STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MITFMicrophthalmia-associated transcription factor. (635 aa)    
Predicted Functional Partners:
TFE3
Transcription factor binding to IGHM enhancer 3.
  
 
0.945
TFEB
Transcription factor EB.
    
0.926
MAPK1
Mitogen-activated protein kinase 1/3.
    
 0.912
TYRP1
Tyrosinase related protein 1.
   
 0.886
BEST1
Bestrophin 1.
      
 0.843
RPE65
Retinoid isomerohydrolase / lutein isomerase.
      
 0.834
DCT
Dopachrome tautomerase.
   
 0.790
KIT
KIT proto-oncogene receptor tyrosine kinase.
   
  
 0.731
EDNRB
Endothelin receptor type B.
   
 
 0.730
SOX10
Transcription factor SOX7/8/10/18 (SOX group E/F).
    
 
 0.701
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.