STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DHFRDihydrofolate reductase. (157 aa)    
Predicted Functional Partners:
TYMS
Thymidylate synthetase.
 
 
 0.999
SHMT1
Serine hydroxymethyltransferase 1.
  
 
 0.993
FPGS
Folylpolyglutamate synthase.
     
 0.993
SHMT2
Serine hydroxymethyltransferase 2.
  
 
 0.991
GART
annotation not available
  
 
 0.981
AMT
Aminomethyltransferase.
  
 
 0.967
MTHFD1L
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like.
  
 
 0.964
MTHFD1
C-1-tetrahydrofolate synthase, cytoplasmic.
  
 
 0.962
MTFMT
Mitochondrial methionyl-tRNA formyltransferase.
  
 
 0.953
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase.
    
 0.951
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.