STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPP1Tripeptidyl peptidase 1. (578 aa)    
Predicted Functional Partners:
GRN
Granulin precursor.
   
 
 0.758
CLN6
Ceroid-lipofuscinosis, neuronal 6, late infantile, variant.
     
 0.757
CLN5
Ceroid-lipofuscinosis neuronal protein 5.
      
 0.756
CLN3
CLN3, battenin.
      
 0.745
TERF2IP
Telomeric repeat-binding factor 2-interacting protein 1.
    
 0.706
CLN8
Ceroid-lipofuscinosis neuronal protein 8.
    
 
 0.700
TBPL1
TATA-box binding protein like 1.
    
 0.680
TMEM106B
Transmembrane protein 106B.
    
 0.641
POT1
Protection of telomeres protein 1.
    
 0.636
PPT1
Palmitoyl-protein thioesterase 1.
   
 
 0.623
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.