STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRRC8ELeucine rich repeat containing 8 family member E. (793 aa)    
Predicted Functional Partners:
LRRC8A
Leucine rich repeat containing 8 family member A.
  
 
0.972
TTYH3
Tweety family member 3.
      
 0.885
TTYH2
Tweety family member 2.
      
 0.734
CLCN2
Chloride voltage-gated channel 2.
      
 0.642
ADGRL1
Adhesion G protein-coupled receptor L1.
    
  0.591
ADGRL2
Adhesion G protein-coupled receptor L2.
    
  0.591
ADGRL3
Adhesion G protein-coupled receptor L3.
    
  0.591
LRRC8B
Leucine rich repeat containing 8 family member B.
  
 
0.589
LRRC8D
Leucine rich repeat containing 8 family member D.
  
 
0.535
BEST1
Bestrophin 1.
      
 0.517
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.