STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LIG1DNA ligase 1. (888 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen.
   
 0.993
FEN1
Flap structure-specific endonuclease 1.
  
 0.987
POLB
DNA polymerase beta.
  
 0.979
APEX1
Apurinic/apyrimidinic endodeoxyribonuclease 1.
  
 
 0.958
ENSEASP00005018189
annotation not available
  
 0.945
XRCC1
X-ray repair cross complementing 1.
   
 0.926
UNG
Uracil DNA glycosylase.
   
  
 0.925
RFC4
Replication factor C subunit 2/4.
   
 0.924
POLD1
DNA polymerase delta 1, catalytic subunit.
   
 0.922
MCM5
Minichromosome maintenance complex component 5.
   
  
 0.913
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.