STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPG21Spastic paraplegia 21 (autosomal recessive, Mast syndrome). (308 aa)    
Predicted Functional Partners:
SPG7
SPG7, paraplegin matrix AAA peptidase subunit.
      
 0.912
SPG11
Spastic paraplegia 11 (autosomal recessive).
      
 0.887
TECPR2
Tectonin beta-propeller repeat-containing protein 2.
      
 0.758
ENSEASP00005008844
annotation not available
      
 0.735
TNFSF15
TNF superfamily member 15.
      
 0.733
GPC3
Glypican 3.
      
 0.692
LTF
Lactotransferrin.
      
 0.666
PAAF1
Proteasomal ATPase associated factor 1.
      
 0.596
ALDH16A1
Aldehyde dehydrogenase 16 family member A1.
      
 0.594
NIPA1
Non imprinted in Prader-Willi/Angelman syndrome 1.
      
 0.592
Your Current Organism:
Equus asinus
NCBI taxonomy Id: 83772
Other names: E. asinus asinus, Equus asinus asinus
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